This systematic review and meta-analysis investigates the relationship between periodontitis and dementia. Researchers analyzed data from multiple studies to determine the association's strength, considering the severity of periodontitis and dementia type. The results indicate a strong correlation between severe periodontitis and an increased risk of dementia, particularly Alzheimer's disease. Less severe periodontitis showed no significant association with dementia. The study highlights the potential for periodontitis management to positively impact dementia prevention.